PURE RUTIN
- Promotes collagen production, improves elasticity, and reduces oxidative stress for healthier-looking skin.*
- Senotherapeutic support: reduces inflammatory signals from senescent "zombie" cells.*
- Shown to regulate blood sugar, blood pressure, and mitochondrial function associated metabolic decline.*
- Promotes reduced clot formation and improved blood flow to counter age and COVID related vascular decline.*
- Backed by preclinical and human research showing benefits for the brain, heart, bones, and immune system.*
Rutin: a Quercetin Glycoside with Unique benefits*
Rutin is a bioflavonoid found in plants like buckwheat, apples, citrus fruits, and green tea. It is best known for its strong antioxidant and anti-inflammatory effects, and is also thought to have antiprotozoal, antibacterial, and aintiviral properties. Chemically, rutin is a glycoside, which means it combines a sugar with a non-sugar component. The non-sugar part is quercetin, another flavonoid with powerful pharmacological properties, while the sugar part is called rutinose. Rutinose itself is made of two sugars, glucose and rhamnose. Rhamnose is unusual because it exists naturally in plants and bacteria as L-rhamnose, but not in humans. Most sugars in nature are the D form, making the L form rare. L-rhamnose does not spike blood sugar and has been considered an indistinguishable substitute for sugar. Unfortunately, exorbitant production costs prevents it from ever being widely available for this use at this time.
Rutin Restores Skin Tissue*
Rutin has shown strong potential for maintaining healthy skin and slowing visible aging. A study published in the International Journal of Molecular Medicine examined its effects both in the lab and in human participants. In lab experiments, rutin boosted collagen production (COL1A1) while reducing enzymes (MMP1) that break down collagen. This suggests it may help preserve skin structure and slow collagen loss. Rutin also displayed strong antioxidant properties, reducing oxidative stress, another major contributor to skin aging. In a clinical trial of 40 participants (ages 30–50), a cream containing rutin was applied for four weeks. The results showed improved skin elasticity and a noticeable reduction in wrinkles, especially around the eyes. These findings indicate that rutin helps protect skin by supporting collagen and reducing oxidative damage, making it a valuable ingredient in anti-aging skincare. [1]
Rutin's Demonstrated Senotherapeutic Potential*
Rutin has shown potential as a senomorphic agent, meaning it can modify the behavior of senescent cells (also called “zombie cells”) without killing them. These aged cells stop dividing but continue to release harmful inflammatory signals known as SASP (senescence-associated secretory phenotype). Accumulation of these cells is a major driver of chronic inflammation, and tissue damage associated with aging. A study in Aging Cell found that rutin reduced SASP factors by disrupting protein interactions that control inflammation. In aged mice, supplementation with rutin lowered systemic inflammation and improved physical performance. The study also suggested rutin may influence the tumor microenvironment, making cancer cells more vulnerable to treatment. These findings highlight rutin’s potential as a powerful, but well tolerated senotherapeutic compound. [2]
In a 2017 study, it was discovered that the likely mechanism behind rutin’s anticancer effects comes from the inhibition of the c-Met kinase enzyme. [3] These proteins have recently been found to serve as an early marker of cellular senescence and might contribute to resistance to apoptosis (programmed cell death) and an increase in senescence-associated secretory phenotype (SASP), making c-Met inhibitors a valuable component in anti-aging applications. Dasatinib has also been shown to indirectly inhibit c-Met by targeting c-Src, a downstream transducer of c-Met signaling. [4] Rutin’s inclusion into NEUROmergence® was to better align the formulation with Dasatinib’s senotherapeutic mechanisms.
Pre-clinical Data on Rutin’s Anti-Aging Potential*
Pre-clinical studies using models such as C. elegans (roundworms) and mice show promising effects of rutin on lifespan and vitality. These models are commonly used in longevity research because of their short lifespans and well-conserved biological pathways. Rutin has been shown to extend lifespan and improve exercise capacity in both worms and mice, suggesting its benefits may translate to humans. [5]
| Model / Measure | Effect of Rutin | Significance |
|---|---|---|
| C. elegans lifespan | Extended lifespan | p < 0.05 |
| C. elegans egg production | Increased number of eggs | p < 0.05 |
| Mouse exercise & motor function | Improved exercise capacity | p < 0.05 |
| Mouse brain oxidative stress (ROS) | Reduced ROS levels | p < 0.05 |
| Mouse brain lipid peroxidation (MDA) | Lowered MDA levels | p < 0.01 |
| Serum & brain antioxidant enzymes (SOD) | Enhanced SOD activity | p < 0.05 |
| Serum & brain antioxidant enzymes (GSH-Px) | Increased GSH-Px activity | p < 0.01 |
Rutin Demonstrates Positive Results in Improving Age-related Metabolic Dysfunction*
A study in Food & Function examined the effects of rutin on metabolic dysfunction in aged rats. Supplementation with rutin significantly improved several metabolic markers commonly affected by aging. These included lower fasting blood glucose and insulin levels, reduced blood pressure, and improved insulin resistance (shown by lower HOMA-IR values). Rutin also enhanced glucose and insulin tolerance, improved mitochondrial function, reduced endoplasmic reticulum stress, and lowered oxidative stress. These results suggest rutin can address inflammation, lipid accumulation, and cellular stress, making it a promising candidate for managing age-related metabolic diseases. [6]
Rutin’s Antithrombotic Potential: Reversing Damage from Advanced Aging and Long COVID*
A landmark study on rutin showed that it can slow clot formation, extend clotting times, and directly inhibit thrombin activity. In live models, rutin prevented acute thromboembolic events triggered by collagen, epinephrine, or thrombin, making it one of the clearest demonstrations of rutin’s antithrombotic power [7]. This is highly relevant to aging, as circulation tends to decline with age. Larger clots and hidden microclots become more common, silently reducing oxygen and nutrient delivery to the brain, heart, and other organs. This vascular damage accelerates memory decline, frailty, and cardiovascular disease [8][9]. By protecting microvascular health, rutin helps support longevity at a fundamental level. The same mechanism applies to long COVID. Multiple studies have identified persistent microclots in patients with ongoing post-viral symptoms. These clots trap inflammatory proteins, block the smallest blood vessels, and reduce oxygen delivery, leading to fatigue, brain fog, and breathlessness [10][11][12]. Rutin’s proven ability to reduce abnormal clotting highlights its potential role in counteracting both age-related decline and long COVID complications.
Furthermore, in a 2021 study, it was shown that rutin can attach very tightly to several important proteins of the COVID-19 virus. By locking itself into these proteins, rutin may stop the virus from working properly and block its ability to spread in the body. The study showed that rutin could potentially inhibit multiple viral proteins at once, including those needed for the virus to copy itself and infect cells. Because rutin is a safe flavonoid already present in many foods and traditional medicines, it may be useful as part of future treatments or combined therapies for COVID-19. [13]
Unlocking the Power of Rutin*
Rutin’s benefits extend across multiple systems of the body. A comprehensive review of studies (see this review) highlights how it protects cells from oxidative stress and inflammation, supports blood vessel function by boosting nitric oxide, promotes brain health and memory, and even encourages bone strength. Together, these effects target many of the processes that decline with age. By supporting circulation, cognitive function, bone health, and inflammation control, rutin stands out as a natural compound with multi-system benefits and strong potential for promoting longevity and resilience as we age. [14]
ATTENTION:
If pregnant, nursing, or trying to conceive, do not use this product. If you take medications, have preexisting conditions, or suffer from allergies of any kind, please consult your physician before taking this, or any other dietary supplements. The information contained on this site has not been evaluated by the Food and Drug Administration. * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
ABOUT MDS LABS
CITATIONS:
[1] Choi SJ, Lee SN, Kim K, Joo da H, Shin S, Lee J, Lee HK, Kim J, Kwon SB, Kim MJ, Ahn KJ, An IS, An S, Cha HJ. Biological effects of rutin on skin aging. Int J Mol Med. 2016 Jul;38(1):357-63. doi: 10.3892/ijmm.2016.2604. Epub 2016 May 24. PMID: 27220601. https://pubmed.ncbi.nlm.nih.gov/27220601/
[2] Liu, H., Xu, Q., Wufuer, H., Li, Z., Sun, R., Jiang, Z., Dou, X., Fu, Q., Campisi, J., & Sun, Y. (2024). Rutin is a potent senomorphic agent to target senescent cells and can improve chemotherapeutic efficacy. Aging Cell, 23, e13921. https://doi.org/10.1111/acel.13921 [3] Elsayed HE, Ebrahim HY, Mohyeldin MM, Siddique AB, Kamal AM, Haggag EG, El Sayed KA. Rutin as A Novel c-Met Inhibitory Lead for The Control of Triple Negative Breast Malignancies. Nutr Cancer. 2017 Nov-Dec;69(8):1256-1271. doi: 10.1080/01635581.2017.1367936. Epub 2017 Oct 30. PMID: 29083228; PMCID: PMC6193555. https://pubmed.ncbi.nlm.nih.gov/29083228/ [4] Sen B, Peng S, Saigal B, Williams MD, Johnson FM. Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer. Clin Cancer Res. 2011 Feb 1;17(3):514-24. doi: 10.1158/1078-0432.CCR-10-1617. Epub 2010 Nov 24. PMID: 21106725; PMCID: PMC3460647. https://pubmed.ncbi.nlm.nih.gov/21106725/ [5] Xinghua L, Yingying H, Shuai W, Guangping L. Anti-aging Effect of Rutin in Caenorhabditis elegans and D-Gal-Induced Aging Mouse Model. Dokl Biochem Biophys. 2023 Dec;513(1):350-354. doi: 10.1134/S1607672923700515. Epub 2023 Dec 8. PMID: 38066322. https://pubmed.ncbi.nlm.nih.gov/38066322/ [6] Li T, Chen S, Feng T, Dong J, Li Y, Li H. Rutin protects against aging-related metabolic dysfunction. Food Funct. 2016 Feb;7(2):1147-54. doi: 10.1039/c5fo01036e. PMID: 26804783. https://pubmed.ncbi.nlm.nih.gov/26804783/ [7] Choi JH, Kim DW, Park SE, Lee HJ, Kim KM, Kim KJ, Kim MK, Kim SJ, Kim S. Anti-thrombotic effect of rutin isolated from Dendropanax morbifera Leveille. J Biosci Bioeng. 2015 Aug;120(2):181-6. doi: 10.1016/j.jbiosc.2014.12.012. Epub 2015 Mar 14. PMID: 25777266. https://pubmed.ncbi.nlm.nih.gov/25777266/ [8] Kaplon, R. E., & Seals, D. R. (2023). Vascular aging and the microcirculation. Antioxidants & Redox Signaling, 38(12–13), 915–933. https://doi.org/10.1089/ars.2023.0365 [9] Ungvari, Z., Tarantini, S., Donato, A. J., & Csiszar, A. (2023). Mechanisms of vascular aging: New perspectives. Journal of Gerontology: Series A, 78(10), 1813–1822. https://pubmed.ncbi.nlm.nih.gov/37742116/ [10] Pretorius, E., Venter, C., Laubscher, G. J., Kotze, M. J., Oladejo, S. O., Watson, L. R., & Kell, D. B. (2021). Persistent clotting protein pathology in long COVID/Post-acute sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin. Cardiovascular Diabetology, 20(1), 172. https://doi.org/10.1186/s12933-021-01359-7 [11] Kell, D. B., & Pretorius, E. (2023). Microclots and fibrinaloid microclots as key drivers of long COVID and related conditions. Frontiers in Immunology, 14, 1177473. https://pmc.ncbi.nlm.nih.gov/articles/PMC10174338/ [12] Ducharme, J. (2022, December 8). Why ‘microclots’ may be a cause of long COVID. Time Magazine. https://time.com/6238147/microclots-long-covid/ [13] Rahman F, Tabrez S, Ali R, Alqahtani AS, Ahmed MZ, Rub A. Molecular docking analysis of rutin reveals possible inhibition of SARS-CoV-2 vital proteins. J Tradit Complement Med. 2021 Mar;11(2):173-179. doi: 10.1016/j.jtcme.2021.01.006. Epub 2021 Jan 22. PMID: 33520682; PMCID: PMC7825826. https://pubmed.ncbi.nlm.nih.gov/33520682/ [14] Al-Dhabi NA, Arasu MV, Park CH, Park SU. An up-to-date review of rutin and its biological and pharmacological activities. EXCLI J. 2015 Jan 9;14:59-63. doi: 10.17179/excli2014-663. PMID: 26535031; PMCID: PMC4614038. https://pmc.ncbi.nlm.nih.gov/articles/PMC4614038/
PURE RUTIN
From youthful skin to vascular protection and long COVID recovery,
research shows rutin supports healthy aging across multiple systems.*
- Promotes collagen production, improves elasticity, and reduces oxidative stress for healthier-looking skin.*
- Senotherapeutic support: reduces inflammatory signals from senescent “zombie” cells.*
- Shown to regulate blood sugar, blood pressure, and mitochondrial function associated metabolic decline.*
- Promotes reduced clot formation and improved blood flow to counter age and COVID related vascular decline.*
- Backed by preclinical and human research showing benefits for the brain, heart, bones, and immune system.*
Rutin: a Quercetin Glycoside with Unique benefits*
Rutin is a bioflavonoid found in plants like buckwheat, apples, citrus fruits, and green tea. It is best known for its strong antioxidant and anti-inflammatory effects, and is also thought to have antiprotozoal, antibacterial, and aintiviral properties. Chemically, rutin is a glycoside, which means it combines a sugar with a non-sugar component. The non-sugar part is quercetin, another flavonoid with powerful pharmacological properties, while the sugar part is called rutinose. Rutinose itself is made of two sugars, glucose and rhamnose.
Rhamnose is unusual because it exists naturally in plants and bacteria as L-rhamnose, but not in humans. Most sugars in nature are the D form, making the L form rare. L-rhamnose does not spike blood sugar and has been considered an indistinguishable substitute for sugar. Unfortunately, exorbitant production costs prevents it from ever being widely available for this use at this time.
Rutin Restores Skin Tissue*
Rutin has shown strong potential for maintaining healthy skin and slowing visible aging. A study published in the International Journal of Molecular Medicine examined its effects both in the lab and in human participants. In lab experiments, rutin boosted collagen production (COL1A1) while reducing enzymes (MMP1) that break down collagen. This suggests it may help preserve skin structure and slow collagen loss.
Rutin also displayed strong antioxidant properties, reducing oxidative stress, another major contributor to skin aging. In a clinical trial of 40 participants (ages 30–50), a cream containing rutin was applied for four weeks. The results showed improved skin elasticity and a noticeable reduction in wrinkles, especially around the eyes. These findings indicate that rutin helps protect skin by supporting collagen and reducing oxidative damage, making it a valuable ingredient in anti-aging skincare. [1]
Rutin’s Demonstrated Senotherapeutic Potential*
Rutin has shown potential as a senomorphic agent, meaning it can modify the behavior of senescent cells (also called “zombie cells”) without killing them. These aged cells stop dividing but continue to release harmful inflammatory signals known as SASP (senescence-associated secretory phenotype). Accumulation of these cells is a major driver of chronic inflammation, and tissue damage associated with aging.
A study in Aging Cell found that rutin reduced SASP factors by disrupting protein interactions that control inflammation. In aged mice, supplementation with rutin lowered systemic inflammation and improved physical performance. The study also suggested rutin may influence the tumor microenvironment, making cancer cells more vulnerable to treatment. These findings highlight rutin’s potential as a powerful, but well tolerated senotherapeutic compound. [2]
In a 2017 study, it was discovered that the likely mechanism behind rutin’s anticancer effects comes from the inhibition of the c-Met kinase enzyme. [3] These proteins have recently been found to serve as an early marker of cellular senescence and might contribute to resistance to apoptosis (programmed cell death) and an increase in senescence-associated secretory phenotype (SASP), making c-Met inhibitors a valuable component in anti-aging applications. Dasatinib has also been shown to indirectly inhibit c-Met by targeting c-Src, a downstream transducer of c-Met signaling. [4] Rutin’s inclusion into NEUROmergence® was to better align the formulation with Dasatinib’s senotherapeutic mechanisms.
Pre-clinical Data on Rutin’s Anti-Aging Potential*
Pre-clinical studies using models such as C. elegans (roundworms) and mice show promising effects of rutin on lifespan and vitality. These models are commonly used in longevity research because of their short lifespans and well-conserved biological pathways. Rutin has been shown to extend lifespan and improve exercise capacity in both worms and mice, suggesting its benefits may translate to humans. [5]
| Model / Measure | Effect of Rutin | Significance |
|---|---|---|
| C. elegans lifespan | Extended lifespan | p < 0.05 |
| C. elegans egg production | Increased number of eggs | p < 0.05 |
| Mouse exercise & motor function | Improved exercise capacity | p < 0.05 |
| Mouse brain oxidative stress (ROS) | Reduced ROS levels | p < 0.05 |
| Mouse brain lipid peroxidation (MDA) | Lowered MDA levels | p < 0.01 |
| Serum & brain antioxidant enzymes (SOD) | Enhanced SOD activity | p < 0.05 |
| Serum & brain antioxidant enzymes (GSH-Px) | Increased GSH-Px activity | p < 0.01 |
Rutin Demonstrates Positive Results in Improving Age-related Metabolic Dysfunction*
A study in Food & Function examined the effects of rutin on metabolic dysfunction in aged rats. Supplementation with rutin significantly improved several metabolic markers commonly affected by aging. These included lower fasting blood glucose and insulin levels, reduced blood pressure, and improved insulin resistance (shown by lower HOMA-IR values).
Rutin also enhanced glucose and insulin tolerance, improved mitochondrial function, reduced endoplasmic reticulum stress, and lowered oxidative stress. These results suggest rutin can address inflammation, lipid accumulation, and cellular stress, making it a promising candidate for managing age-related metabolic diseases. [6]
Rutin’s Antithrombotic Potential: Reversing Damage from Advanced Aging and Long COVID*
A landmark study on rutin showed that it can slow clot formation, extend clotting times, and directly inhibit thrombin activity. In live models, rutin prevented acute thromboembolic events triggered by collagen, epinephrine, or thrombin, making it one of the clearest demonstrations of rutin’s antithrombotic power [7].
This is highly relevant to aging, as circulation tends to decline with age. Larger clots and hidden microclots become more common, silently reducing oxygen and nutrient delivery to the brain, heart, and other organs. This vascular damage accelerates memory decline, frailty, and cardiovascular disease [8][9]. By protecting microvascular health, rutin helps support longevity at a fundamental level.
The same mechanism applies to long COVID. Multiple studies have identified persistent microclots in patients with ongoing post-viral symptoms. These clots trap inflammatory proteins, block the smallest blood vessels, and reduce oxygen delivery, leading to fatigue, brain fog, and breathlessness [10][11][12]. Rutin’s proven ability to reduce abnormal clotting highlights its potential role in counteracting both age-related decline and long COVID complications.
Furthermore, in a 2021 study, it was shown that rutin can attach very tightly to several important proteins of the COVID-19 virus. By locking itself into these proteins, rutin may stop the virus from working properly and block its ability to spread in the body. The study showed that rutin could potentially inhibit multiple viral proteins at once, including those needed for the virus to copy itself and infect cells. Because rutin is a safe flavonoid already present in many foods and traditional medicines, it may be useful as part of future treatments or combined therapies for COVID-19. [13]
Unlocking the Power of Rutin*
Rutin’s benefits extend across multiple systems of the body. A comprehensive review of studies (see this review) highlights how it protects cells from oxidative stress and inflammation, supports blood vessel function by boosting nitric oxide, promotes brain health and memory, and even encourages bone strength. Together, these effects target many of the processes that decline with age.
By supporting circulation, cognitive function, bone health, and inflammation control, rutin stands out as a natural compound with multi-system benefits and strong potential for promoting longevity and resilience as we age. [14]
ATTENTION:
If pregnant, nursing, or trying to conceive, do not use this product. If you take medications, have preexisting conditions, or suffer from allergies of any kind, please consult your physician before taking this, or any other dietary supplements. The information contained on this site has not been evaluated by the Food and Drug Administration.
* These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
ABOUT MDS LABS
CITATIONS:
[1] Choi SJ, Lee SN, Kim K, Joo da H, Shin S, Lee J, Lee HK, Kim J, Kwon SB, Kim MJ, Ahn KJ, An IS, An S, Cha HJ. Biological effects of rutin on skin aging. Int J Mol Med. 2016 Jul;38(1):357-63. doi: 10.3892/ijmm.2016.2604. Epub 2016 May 24. PMID: 27220601.
https://pubmed.ncbi.nlm.nih.gov/27220601/
[2] Liu, H., Xu, Q., Wufuer, H., Li, Z., Sun, R., Jiang, Z., Dou, X., Fu, Q., Campisi, J., & Sun, Y. (2024). Rutin is a potent senomorphic agent to target senescent cells and can improve chemotherapeutic efficacy. Aging Cell, 23, e13921.
https://doi.org/10.1111/acel.13921
[3] Elsayed HE, Ebrahim HY, Mohyeldin MM, Siddique AB, Kamal AM, Haggag EG, El Sayed KA. Rutin as A Novel c-Met Inhibitory Lead for The Control of Triple Negative Breast Malignancies. Nutr Cancer. 2017 Nov-Dec;69(8):1256-1271. doi: 10.1080/01635581.2017.1367936. Epub 2017 Oct 30. PMID: 29083228; PMCID: PMC6193555.
https://pubmed.ncbi.nlm.nih.gov/29083228/
[4] Sen B, Peng S, Saigal B, Williams MD, Johnson FM. Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer. Clin Cancer Res. 2011 Feb 1;17(3):514-24. doi: 10.1158/1078-0432.CCR-10-1617. Epub 2010 Nov 24. PMID: 21106725; PMCID: PMC3460647.
https://pubmed.ncbi.nlm.nih.gov/21106725/
[5] Xinghua L, Yingying H, Shuai W, Guangping L. Anti-aging Effect of Rutin in Caenorhabditis elegans and D-Gal-Induced Aging Mouse Model. Dokl Biochem Biophys. 2023 Dec;513(1):350-354. doi: 10.1134/S1607672923700515. Epub 2023 Dec 8. PMID: 38066322.
https://pubmed.ncbi.nlm.nih.gov/38066322/
[6] Li T, Chen S, Feng T, Dong J, Li Y, Li H. Rutin protects against aging-related metabolic dysfunction. Food Funct. 2016 Feb;7(2):1147-54. doi: 10.1039/c5fo01036e. PMID: 26804783.
https://pubmed.ncbi.nlm.nih.gov/26804783/
[7] Choi JH, Kim DW, Park SE, Lee HJ, Kim KM, Kim KJ, Kim MK, Kim SJ, Kim S. Anti-thrombotic effect of rutin isolated from Dendropanax morbifera Leveille. J Biosci Bioeng. 2015 Aug;120(2):181-6. doi: 10.1016/j.jbiosc.2014.12.012. Epub 2015 Mar 14. PMID: 25777266.
https://pubmed.ncbi.nlm.nih.gov/25777266/
[8] Kaplon, R. E., & Seals, D. R. (2023). Vascular aging and the microcirculation. Antioxidants & Redox Signaling, 38(12–13), 915–933.
https://doi.org/10.1089/ars.2023.0365
[9] Ungvari, Z., Tarantini, S., Donato, A. J., & Csiszar, A. (2023). Mechanisms of vascular aging: New perspectives. Journal of Gerontology: Series A, 78(10), 1813–1822.
https://pubmed.ncbi.nlm.nih.gov/37742116/
[10] Pretorius, E., Venter, C., Laubscher, G. J., Kotze, M. J., Oladejo, S. O., Watson, L. R., & Kell, D. B. (2021). Persistent clotting protein pathology in long COVID/Post-acute sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin. Cardiovascular Diabetology, 20(1), 172.
https://doi.org/10.1186/s12933-021-01359-7
[11] Kell, D. B., & Pretorius, E. (2023). Microclots and fibrinaloid microclots as key drivers of long COVID and related conditions. Frontiers in Immunology, 14, 1177473.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10174338/
[12] Ducharme, J. (2022, December 8). Why ‘microclots’ may be a cause of long COVID. Time Magazine.
https://time.com/6238147/microclots-long-covid/
[13] Rahman F, Tabrez S, Ali R, Alqahtani AS, Ahmed MZ, Rub A. Molecular docking analysis of rutin reveals possible inhibition of SARS-CoV-2 vital proteins. J Tradit Complement Med. 2021 Mar;11(2):173-179. doi: 10.1016/j.jtcme.2021.01.006. Epub 2021 Jan 22. PMID: 33520682; PMCID: PMC7825826.
https://pubmed.ncbi.nlm.nih.gov/33520682/
[14] Al-Dhabi NA, Arasu MV, Park CH, Park SU. An up-to-date review of rutin and its biological and pharmacological activities. EXCLI J. 2015 Jan 9;14:59-63. doi: 10.17179/excli2014-663. PMID: 26535031; PMCID: PMC4614038.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4614038/
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