By mitigating oxidative stress and reducing inflammation, Lupeol can help combat the underlying mechanisms that accelerate aging. Oxidative stress leads to cellular damage and aging, while chronic inflammation is associated with a myriad of age-related diseases such as arthritis, Alzheimer's, cardiovascular disease, and diabetes.
Furthermore, research indicates that Lupeol may have the ability to enhance skin health by modulating the expression of enzymes involved in the degradation of the skin's extracellular matrix. This can potentially reduce wrinkles and improve skin elasticity.
Additionally, studies have suggested that Lupeol may have a role in promoting longevity by impacting cellular senescence, a process where cell division stops as cells age and accumulate damage. By potentially delaying this process, Lupeol is thought to extend cell health and vitality.
Lupeol has been shown to support the inhibition of CDK1, CDK2, CDK4, CDK5, and CDK6 kinase enzymes, and activate MAPK Kinase enzymes.
Sophora flavescens, or Ku Shen, is used in traditional Chinese medicine, and holds potential for anti-aging due to its various bioactive compounds, including Lupeol, an active pentacyclic triterpenoid. Lupeol exhibits a broad spectrum of pharmacological properties, which include anti-inflammatory, antioxidant, and potential anticancer effects.
By mitigating oxidative stress and reducing inflammation, Lupeol can help combat the underlying mechanisms that accelerate aging. Oxidative stress leads to cellular damage and aging, while chronic inflammation is associated with a myriad of age-related diseases such as arthritis, Alzheimer’s, cardiovascular disease, and diabetes.
Furthermore, research indicates that Lupeol may have the ability to enhance skin health by modulating the expression of enzymes involved in the degradation of the skin’s extracellular matrix. This can potentially reduce wrinkles and improve skin elasticity.
Additionally, studies have suggested that Lupeol may have a role in promoting longevity by impacting cellular senescence, a process where cell division stops as cells age and accumulate damage. By potentially delaying this process, Lupeol is thought to extend cell health and vitality.
Lupeol has been shown to support the inhibition of CDK1, CDK2, CDK4, CDK5, and CDK6 kinase enzymes, and activate MAPK Kinase enzymes.
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