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MDS Labs® Full Spectrum Senna Leaf Extract 15mg Capsules

$28.50





 

 

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Sku: SENN-015-30
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Senna, derived from the leaves and fruit of the Senna plant, is primarily known for its laxative properties, attributed to the presence of compounds called sennosides. These compounds stimulate the lining of the bowel, which aids in alleviating constipation, an issue that can become more prevalent with age. Maintaining a healthy digestive system is crucial for the overall health and well-being of the body.

Our Senna supplement is a unique 50:1 extract, standardized to 20% Sennocide B, which is believed to be one of the few natural ingredients that can act as an inhibitor of PDGF, and PDGFR-β pathways. PDGF and PDGFR-β are known as platelet-derived growth factors. These tyrosine kinases have important functions in the development of connective tissue. The detailed structural understanding of PDGF-PDGFR signaling has provided a template that can aid therapeutic intervention to counteract the aberrant signaling of this normally silent pathway, especially in proliferative diseases such as cancer.

Enhanced PDGF-PDGRF signaling is considered abnormal, except when happening briefly during wound repair. Inhibiting this pathway on a temporary basis is thought to be beneficial in the treatment of many diseases, and is one of the key enzymes targeted by both Imatinib and Dasatinib. This is thought to be an important component of the ground-breaking D+Q treatment.

The use of Senna dates back to 3150 BCE, where its residue has been found in Egyptian pottery jars. While generally consumed as a tea, these artifacts suggest it was preserved and used as a medicated wine, and taken as powders, decoctions and syrups.

Senna, derived from the leaves and fruit of the Senna plant, is primarily known for its laxative properties, attributed to the presence of compounds called sennosides. These compounds stimulate the lining of the bowel, which aids in alleviating constipation, an issue that can become more prevalent with age. Maintaining a healthy digestive system is crucial for the overall health and well-being of the body.

Our Senna supplement is a unique 50:1 extract, standardized to 20% Sennocide B, which is believed to be one of the few natural ingredients that can act as an inhibitor of PDGF, and PDGFR-β pathways. PDGF and PDGFR-β are known as platelet-derived growth factors. These tyrosine kinases have important functions in the development of connective tissue. The detailed structural understanding of PDGF-PDGFR signaling has provided a template that can aid therapeutic intervention to counteract the aberrant signaling of this normally silent pathway, especially in proliferative diseases such as cancer.

Enhanced PDGF-PDGRF signaling is considered abnormal, except when happening briefly during wound repair. Inhibiting this pathway on a temporary basis is thought to be beneficial in the treatment of many diseases, and is one of the key enzymes targeted by both Imatinib and Dasatinib. This is thought to be an important component of the ground-breaking D+Q treatment.

The use of Senna dates back to 3150 BCE, where its residue has been found in Egyptian pottery jars. While generally consumed as a tea, these artifacts suggest it was preserved and used as a medicated wine, and taken as powders, decoctions and syrups.

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